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NSC 377071
CAS No. 26097-80-3
NSC 377071( NSC-377071 | NSC377071 | Cambendazole )
Catalog No. M13794 CAS No. 26097-80-3
NSC 377071 (NSC-377071, NSC377071, Cambendazole) is a novel ATG4B antagonist that inhibits autophagy, with no effect on mTOR and PI3K activities.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 45 | In Stock |
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| 5MG | 61 | In Stock |
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| 10MG | 115 | In Stock |
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| 25MG | 178 | In Stock |
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| 50MG | 306 | In Stock |
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| 100MG | 487 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameNSC 377071
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NoteResearch use only, not for human use.
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Brief DescriptionNSC 377071 (NSC-377071, NSC377071, Cambendazole) is a novel ATG4B antagonist that inhibits autophagy, with no effect on mTOR and PI3K activities.
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DescriptionNSC 377071 (NSC-377071, NSC377071, Cambendazole) is a novel ATG4B antagonist that inhibits autophagy, with no effect on mTOR and PI3K activities; directly inhibits cellular ATG4B activity induced by starvation or rapamycin and suppresses the lipidation of LC3B and autophagosome formation in response to starvation, suppresses Saos-2 osteosarcoma growth in vivo.
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In Vitro——
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In Vivo——
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SynonymsNSC-377071 | NSC377071 | Cambendazole
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PathwayAutophagy
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TargetAtg
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number26097-80-3
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Formula Weight302.352
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Molecular FormulaC14H14N4O2S
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Purity>98% (HPLC)
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SolubilityDMSO: Soluble （ < 1 mg/ml refers to the product slightly soluble or insoluble )
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SMILESO=C(OC(C)C)NC1=CC=C2C(N=C(C3=CSC=N3)N2)=C1
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Chemical NamePropan-2-yl N-[2-(1,3-thiazol-4-yl)-3H-benzimidazol-5-yl]carbamate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Akin D, et al. Autophagy. 2014;10(11):2021-35.
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